Summary: Fine Needle Aspiration Biopsies for Gene Expression Ratio-based Diagnostic and Predictive Tests in Malignant Pleural Mesothelioma.
CONCLUSIONS: Sufficient RNA can be extracted from most FNA biopsies to perform gene expression molecular tests. In particular, we show that the gene expression ratio algorithms performed well when applied to diagnosis and prognosis in MPM. This study provides support for the development of additional RNA molecular tests that may enhance the utility of FNA in the management of other solid cancers
CONCLUSIONS: Sufficient RNA can be extracted from most FNA biopsies
to perform gene expression molecular tests. In particular, we show
that the gene expression ratio algorithms performed well when
applied to diagnosis and prognosis in MPM. This study provides
support for the development of additional RNA molecular tests that
may enhance the utility of FNA in the management of other solid
cancers
Date Published: Nov 17, 2010 - 9:00 pm