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Feed: The Arthritic Knee - AggScore: 72.7



Knee Arthritis Treatment Advances

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The good news is that because osteoarthritis is affecting more and more people, there is more money to be made so more is spent on research.

Around the world, scientists are all looking for the 'Holy Grail' of osteoarthritis treatment - the ability to re-grow articular cartilage.

The bad news is that despite much effort, we are still some way off a simple solution.
Autologous Chondrocyte Implanting is currently being used to treat areas lacking articular cartilage. This involves multiple operations. Firstly some cartilage cells are harvested via key hole surgery. These are grown in a laboratory before being implanted to cover the defect in the second procedure. Results vary depending on the size and location of the original lesion. It is also costly, and has a lengthy rehabilitation.

Scientists are looking for a simple way to re-grow cartilage. One that can be administered via injection or a single operation.

A new study out of the U.S. has had some promising results using a nanofiber gel in combination with a microfracture technique. The success has so far only been achieved on animal models but it offers hope for the future. This type of treatment is minimally invasive and just what we are looking for. Lets hope the follow up studies are positive as well.

See the full article here.


Date Published: Feb 16, 2010 - 3:59 am

Knee Cartilage or Meniscus?

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Is knee cartilage the same as the meniscus?

This is a common area of confusion when discussion knee problems with a doctor. The confusion is due to doctors using different terms to everyday people.

From a doctors point of view, you have both in your knee. Hopefully anyway.

What is a meniscus?

You have two menisci in each knee. One on the inside of the knee (medial meniscus) and one on the outside (lateral meniscus). Each is a roughly 'C' shaped piece of cartilage that acts as a shock absorber. It has a wedge shape when profiled that helps to contribute to joint stability. The meniscus can be torn by twisting activities and is a common sports injury. This is commonly called a 'torn cartilage'.

What does a doctor mean by cartilage?
To avoid confusion (among themselves only it appears) doctors always refer to 'meniscus' when appropriate, saving the word 'cartilage' for use when discussing Articular Cartilage.
Articular cartilage is the smooth lining of our joints that allows us to move freely without pain, over many years and while weight bearing. As you can imagine, to do this task it is very hard and does not tear like a meniscus. It does however wear away over time or as a result of injury. This wearing the articular cartilage is what we call osteoarthritis.

Are they linked?
Since the meniscus protects the joint by absorbing shock, any injury to it that results in its full or partial removal during surgery increases the risk of osteoarthritis.
These two structurally different types of cartilage work as a team to allow movement and protect the bones of the leg. Losing one or both can have serious consequences.



Date Published: Feb 01, 2010 - 7:17 pm

Hyaluronic Acid - Can it help after Arthroscopy?

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Hyaluronic Acid has been shown to have limited success when used in isolation to treat osteoarthritis. It helps some but not all people, and its benefits may be short lived.

A new study has looked at the use of Hyaluronic Acid after knee arthroscopy. The results of a Weill Medical College investigation showed that patients receiving a series of three injections after their knee surgery had less pain and increased mobility on follow up at 3 and 6 months.

Points to consider:

Knee arthroscopy for osteoarthritis has been shown to be of little benefit unless mechanical symptoms of meniscal tears exist.

The study was limited by a small sample size. A much larger study is required before any benefit can be confirmed.

Having three injections after surgery is likely to slightly increase the risk of infection. Any benefit would need to be large enough to offset this increased risk.


It will be interesting to see what future research reveals.

Date Published: Jan 31, 2010 - 2:19 pm
Trouble Sleeping Due To Knee Arthritis?

A common feature of osteoarthritis is pain at night that restricts sleep.

This is usually made worse if you have been particularly active during the day. The reason sleeping becomes an issue is that the lack of movement we do in bed causes stiffness in the joint. Once a joint is stiff, any small movements we do in adjusting our sleeping position become very painful. This wakes us up - often for only a few seconds as a quick bit of movement eases the pain - then back to sleep we go and the cycle repeats. In the early stages, many people don't wake enough to remember the episode and wonder why they are so tired the next day. As the pain and stiffness get worse the amount of movement required to ease the pain increases and movement as a remedy becomes less effective.

Medication becomes an important tool in these situations, as lack of sleep has an extremely negative effect on our mental well being. There is a reason sleep deprivation is used as torture.

What advice do I have to maximize sleep?

1) Firstly don't fall into the trap of doing less activity during the day in the hope of getting more sleep at night. This will lead to increased stiffness and a bigger problem.

2) Spend the time with your Doctor to find which drug or combination of drugs works for you. Due to our differing physical characteristics, certain drugs work better on some people than others.

3) Try using heat. Ice is used for acute sporting injuries but heat helps stiffness in chronic conditions. Many find that a nice hot bath or shower just before bed will increase the amount of sleep they get in before waking for the first time.

4) Some people find that the affected knee is very sensitive to light touch - especially from the occasional bump from the other knee. Try a pillow between the knees or a specifically designed pad if you tend to move about in your sleep.



Date Published: Jan 24, 2010 - 1:54 am
Simple Knee Arthritis Treatments

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New technology and possible treatment advancements often receive a lot of press coverage but later prove to be ineffective. Everyone is looking for a safe and effective treatment that works for everyone but this is proving elusive.

New research has looked at basic treatments and found some of the simple things are surprisingly effective.

Looking at adults between the ages of 35 and 64 with knee osteoarthritis, the study compared a strengthening program, a self management program, and a combination of both. Participants were followed over a two year period and were tested with variety of outcome measures.

Many people would think that these types of treatment would not significantly help their arthritis but the results showed that all groups improved in every test. The tests included leg press strength, range of motion, balance, stairs, work capacity and reported pain.

We should all start our management of osteoarthritis by implementing the simple treatments that have been shown to improve quality of life. After that we can look for further treatments.

The full research article can be found here


Date Published: Jan 18, 2010 - 1:46 pm
Osteoarthritis - A Battle of Attrition

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Osteoarthritis is not an acute condition.

There will be good days and bad, but it is a long term, degenerative condition that needs to be addressed with an appropriate strategy.

As a general rule, the longer a condition lasts, the less likely a "quick fix"exists. A 30 year history of osteoarthritis is not going to be fixed by a pill.

The reason I bring this up is that long term diseases take long term commitment to influence. You do not have to accept the inevitability of osteoarthritis, but you have to realize that to alter the course of this disease, long term lifestyle changes are required.

There are many treatments that claim to help osteoarthritis, but you will find that the non-surgical ones that have been shown to help take time to show their benefit. Weight loss and quadriceps strengthening increase mobility and decrease pain but usually take a minimum of 6 weeks to take effect.

The "take home message" here is that you can have a positive effect on your knee arthritis but you need to get serious and treat it like a job. Sign yourself up for two months of hard work then reassess your condition. I think you will be pleasantly surprised.


Date Published: Dec 19, 2009 - 4:00 am
Knee Replacement Surgery - Should You Have Both Done At Once?

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If you are unfortunate enough to require a knee replacement on both legs, occasionally surgeons will offer to do them simultaneously. This is a big decision to make as it is obviously harder to rehabilitate when you don't have a "good" leg to rely upon.

Why would anyone do this?

Well, there are some advantages. The total recovery time is usually much quicker having them done together than the total of two separate occasions. This makes it an attractive proposition for people with a hectic schedule.
You will only have to have one anesthetic, although it will be of significantly longer duration. It is also likely to cost much less than two separate surgical interventions.

The main problem is a more difficult initial phase of the recovery. For this reason surgeons pick their candidates carefully.
Simultaneous total knee replacements will only be offered to low risk patients. They need to be free of upper limb problems due to the increased initial load on the arms when ambulating. Social factors are important also. Living with an able bodied partner in level accommodation is easier than living alone on the 5th floor with no lift. Medical complications and risk factors such as cardiovascular disease, diabetes and obesity will often see a surgeon recommend one knee at a time.

If the possibility of 2 knee replacements is offered to you, discuss it with your family,and consider how much support you will receive in the short term.

There are benefits to be had, but they are best suited for highly motivated, low risk individuals with a good support network.

Date Published: Nov 30, 2009 - 2:11 am
Knee Arthritis Pain Medication

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When you are relying on medication to get you through the day it is important to have a good understanding of what is safe. There is no substitute for trained medical advice that is specific to your medical history. None of us are the same and some drugs work better for some people than they do for others.

Again, having a basic understanding can help you ask the right questions.

Paracetamol is a common arthritis drug. Many people do not give it credit as it is readily available over the counter but studies have shown it to be effective in treating arthritic pain. It has relatively few drug interactions and side effects but it is important to stick to the recommended amount as the overdose level is not particularly well distanced from the therapeutic dose.

NSAIDs or Non Steroidal Anti-Inflammatory Drugs are also typically used to combat arthritic knee pain. Many of these drugs are also available over the counter. They do have some common side effects to be aware of such as exacerbation of asthma and gastrointestinal tract bleeding. They should always be taken after food for this reason. Aspirin is a member of this family of drugs. It is usually safe to take these drugs in combination with paracetamol.

Opioids are another category of common knee arthritis medications. Codeine (a.k.a. Tylenol 3) is often sold as a combined preparation with paracetamol. Codeine is a strong pain killer but can have serious consequences if overdosed and can cause constipation even at recommended levels. Care should be taken combining any codeine product with paracetamol as it is so common for the codeine tablet to contain paracetamol that any additional paracetamol can lead to overdose and liver damage.

If you are not happy with the relief your current analgesia is delivering, discuss your options with your physician or pharmacist. Get specialist advice as the interactions between drugs are extremely complicated and your personal medical history needs to be taken into account. Some drugs can be combined to give extra relief but this process needs to be overseen by a professional.

Date Published: Nov 26, 2009 - 4:18 am
Waiting for a Total Knee Replacement?

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Unfortunately, for many people it will eventually get to the stage where there only thing that is going to help is a total knee replacement ( also called a total knee arthroplasty).

It is not uncommon for there to be a waiting period between when the decision is made and when the operation occurs. This may be a matter of weeks or, in the case of public health systems, many months.
Once you have agreed to a knee replacement your next question should be: What can I do between now and the surgery?

1) Remain as active as possible: Don't cease all painful activity while you wait. Continue as best you can despite the pain. Decreased activity can lead to loss of muscle strength and increased knee stiffness.

2) Work those quads: The stronger your quadriceps muscle, the easier it will be for you to recover from the surgery. Even if your wait is only a few weeks, improvements can be made.

3) Educate yourself about Deep Venous Thrombosis, a potential complication of surgery. Learn what you need to do to decrease your risk. This link goes to my article on DVT

4) Prepare your house: Remove trip hazards such as rugs. Remove clutter. Do any jobs that will be difficult after your operation.

5) Practice Crutches: If you have never used crutches before, consider learning how to uses them BEFORE your operation. Try stairs with crutches with and without a rail.

These are all simple, easy things to do and they can make your recovery much more pleasant. Don't waste the time before your operation - use it to your advantage.

Date Published: Nov 03, 2009 - 8:56 pm
Unicompartmental Knee Replacement

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What is the point of replacing only half of the knee?

There has been a change in attitude amongst surgeons in the last few decades. The old, aggressive surgical practices of big operations with big incisions has been replaced by minimally invasive techniques and a philosophy of doing the smallest amount possible to achieve a result.

A good example of this is cartilage tears in the knee. The old way was a large incision and complete removal of the meniscus. Today only the torn part is removed and this is done as a day case via key hole surgery.

Knee replacements are the same. Surgeons began to ask: "Why are we replacing the whole knee when only one compartment is worn?"

Due to the angulation that occurs in arthritis - either bow-legged or knock-kneed - all of the weight goes on the worn half of the knee while the other half gets a rest. This means it is often in very good condition.
Half knee replacements are only suitable if there is a good enough surface on the less worn side of the knee.
One of the advantages of unicompartmental knee replacements is that you can still have a full knee replacement later. It is more difficult to perform but not as troublesome as a revision total knee replacement.
There have been some concerns over the lifespan of half knee replacements. It has been argued that their shorter life is a result of them being used on much younger people who demand more from the implant.
There are many factors to consider, so discuss your personal medical history with your consultant to see if a unicompartmental knee is the right choice for you.


Date Published: Oct 20, 2009 - 5:48 pm
Why do Knee Replacements hurt more than Hip Replacements?

Although not always the case, most people who have had both a knee and hip replacement report that the knee is the more painful.

There are a few reasons for this, the main one being the location of the incision.

There are multiple ways of approaching a hip replacement but all of them result in the incision being 'out of the way'. A knee replacement has the incision straight down the front of the knee. This has an effect on the rehabilitation.

To prevent the knee from stiffening, the knee must be quickly exercised. This means bending the knee and stretching the skin around the incision. This is responsible for a lot of the post-operative pain. After a hip replacement, you are not required to do movements that stretch the scar, in fact you are told to avoid them.

This is why I tell people you can be a little lazy and do OK after a hip replacement, but to get a good result from a knee replacement, you are going to have to work. The pain is something that gets in the way but should be seen as a temporary obstacle to years of pain free walking.

You should be going into a knee replacement operation focused and motivated. It will be a few weeks of toil for the greater good. I have always found that those who have put up with the pain of an arthritic knee for years manage with ease. At least this pain is because of an operation that is going to help. That is much easier to deal with than the pain of arthritis that gains you nothing.

Date Published: Oct 12, 2009 - 3:10 am
Alternative Supplements - What else is there besides Glucosamine and Chondroitin?

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As the evidence mounts that Glucosamine and Chondroitin are not going to help everyone, are there other supplements out there that may help relieve the pain of knee arthritis?

Before going into a few options I repeat my advice that:



1) It doesn't matter what studies on other people have shown, if it works for you, go for it.
BUT
2) If it doesn't work for you after a reasonable period of time, save your money. (If a product is going to help, you should know within 3 months).

So, what else is out there?

Firstly there is Cetyl Myristoleate, also known (thankfully) as CM8. This can be bought combined with glucosamine in tablet form. There has been research into the effect of CM8 and there have been some positive findings. More research is currently in the pipeline so hopefully more positive results to follow. It is likely it will help some but not all arthritis sufferers so it is worth a try but remember - you are only giving a supplement 3 months to prove itself.
CM8 can be bought online under the trade name Flexcin

The second alternative is a natural product based on the Mediterranean diet. Researchers have long studied people from the area due to their lower rates of heart disease and stroke. What many are unaware of is that they also have healthier joints for their age. There are supplements available that take key components of the Mediterranean diet and combine in one tablet. These do not contain any Glucosamine or Chrondroitin are are extremely unlikely to have any side effects. Some will promise results in days but the usual couple of months is sensible to accurately judge if a product is going to be of benefit to you.
Natural Joint Supplement is one such product.

Despite plenty of conflicting evidence about the effectiveness of supplements I continue to see people who swear by them. Finding a non-pharmacological supplement that helps your arthritis is of great benefit but natural variation plays a role - you may be one of the lucky ones, you may not. My advice is to sensibly try out a few supplements giving them 3 months (and 3 months only) to show they work for you. Do not take multiple supplements simultaneously - if it works you won't know which one is beneficial and which one is not.

Only continue past 3 months if there is a measurable improvement in your symptoms. If you are not sure after 3 months, stop taking the supplement and see if your symptoms increase over the coming weeks, if they do, you know it was working.

Good luck!


Date Published: Sep 23, 2009 - 11:32 pm
Knee Braces for Arthritis - Can you fit them yourself?

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That depends....

The incentive is the cost.
You can pick up braces online much cheaper than you can elsewhere. Sizing isn't a problem as online retailers instruct you on what measurements are required to pick the correct size.
For simple braces like pull on sleeves and the classical hinged knee brace, their simplicity makes then well suited to online sales.

More complicated items such as the new generation of offloading brace are more difficult to pull out of a box and work out straight away. Often you may be able to find a physical therapist with some experience of these braces to give you a hand.

Customer service at online retailers are used to enquiries and are also a good place to start.

When you buy a brace from a regular store the extra price covers things such as fitting and face to face instructions. You need to weight up the savings versus the loss of the extra service when buying online.

If a shop doesn't offer fitting then you will be much better off buying on the internet. The Brace Shop is a good place to get an idea of what is available.

Date Published: Sep 20, 2009 - 5:11 am
Basic Exercises for Severe Osteoarthritis

The big problem with exercising for severe arthritis is that everything hurts and seems to make things worse.  You quickly become discouraged and give up. Sound familiar?
If you have very bad arthritis and all of the normal exercises done in weight bearing aggravate your knee, it is time to take a step back.

The following exercise should not be the starting point for everyone. You should start with the best exercises you can manage. The following will be too easy for some and they would get quicker results with tougher exercises.

For those in a lot of pain.......

There are 2 things you can do to exercise and remove some of the strain from you knees.
  1. Do non-weight bearing exercise
  2. Do exercises that involve little or no movement of the knee.
These are the two things that hurt so lets take them out of the equation.

Your starting exercise is The Straight Leg Raise.

Technique:

  • Lie on your back
  • Bend the opposite knee up a little and rest the foot down. This is your starting position. One leg up, one leg out straight.
  • Lift your leg up into the air keeping it as straight as possible. Slowly lower the leg back down in a controlled manner. Do not let it flop.
  • Repeat
The aim is not to see how high you can lift your leg. The aim is to fatigue the muscle so it does not matter if you only lift it a few inches. Initially, the lowering to the bed will be in a smooth arc. The muscle will quickly fatigue and you will notice this lowering becoming increasingly jerky. Once you are struggling to control the leg it is time for a rest.

Below is a video of the straight leg raise. If you have arthritis in both knees you are unlikely to be able to bend the non-exercising knee this much. Just find a comfortable position. You also do not need to lift your leg this high. This instructional video is for knee replacement surgery but the exercise is valid for non-operated knees as well. These exercises should not increase your usual knee pain. You will hopefully get the tired ache of fatigued muscles but that it sit.




Date Published: Sep 03, 2009 - 12:25 am
Squats causing pain - What are you doing wrong?

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Building up the quadriceps muscles protects the knee joint, slows the progression of osteoarthritis, and can decrease pain.
Squats are one of the more popular quads exercises but many people try them and quickly stop when the cause an increase in pain.
Squats are a common gym exercise but you need to do squats differently if you have osteoarthritis. Like any exercises for arthritis, it is important to do them in a pain free range of motion.
Everyone's knees are different so you may need to do a little trial and error but the following points should help:
  • When starting squats you should be doing shallow squats. Very shallow squats. This means your head should drop only 1 or 2 inches throughout the squat. Deep squats puts a lot of pressure on the knee and are nearly guaranteed to cause you pain.
  • When extending the knees after a squat you should not completely straighten you knee. Again, this is likely to cause aggravation.
  • Your aim is to fatigue the muscle without increasing your pain. The muscle is fatigued when it starts to wobble a little. 
  • Do squats slowly. You will find this harder and fatigue the muscle quicker. Aim to do your squats at roughly the speed you breathe.
  • You will usually be able to fatigue the quads in less than a minute. If you have to do more than 30 or 40 to fatigue the muscle, make the squats more difficult. You can do this by doing one legged squats. Keep them shallow and slow and hold onto something for support.
  • Since it only takes a minute to do, you can integrate these exercises into your everyday routine.  While you boil the kettle, squat. Toast on? Squats. On the phone, waiting for a lift, brushing your teeth - do all of these and you will be building strength without aggravation before you know it. Every time you fatigue you are sending a message to your brain to build more muscle. It doesn't matter how old you are, if you use them more, they get bigger, you use them less, they get smaller.


Date Published: Aug 28, 2009 - 4:42 pm
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